Could There Be More Contributing To Your Symptoms Than IBS Alone?

One of the biggest things I've learned through my own journey with coeliac disease, IBS, and gut health is that a diagnosis doesn't automatically get rid of the symptoms. IBS is a real and recognised condition. However, it is increasingly understood as a disorder involving complex interactions between the gut, nervous system, immune system, microbiome, and digestive function. In fact, research published in Nature Reviews Gastroenterology & Hepatology suggests that IBS is not a single disease with a single cause. Instead, multiple factors can contribute to symptom development, which may explain why two people with IBS can experience completely different symptoms and respond to completely different interventions.

This is why, when clients come to me with bloating, abdominal discomfort, constipation, diarrhoea, or food sensitivities, I'm often interested in exploring what may be contributing to those symptoms rather than focusing solely on the IBS label.

Could SIBO Be Contributing?

One area that has received significant attention in recent years is Small Intestinal Bacterial Overgrowth (SIBO). SIBO occurs when excessive bacteria are present within the small intestine, where bacterial populations are normally lower than in the large intestine.

Symptoms can include:

  • Bloating

  • Excessive gas

  • Abdominal discomfort

  • Diarrhoea

  • Constipation

  • Feeling unusually full after meals

A review published in Gut and Liver found that SIBO appears to be more common in some people diagnosed with IBS, particularly those experiencing bloating and altered bowel habits.

While not everyone with IBS has SIBO, and not everyone with SIBO has IBS, it highlights how bacterial overgrowth may be one factor contributing to symptoms in certain individuals.

Is Your Digestive System Breaking Food Down Properly?

Digestion is far more complex than most people realise. Before nutrients can be absorbed, food must first be broken down mechanically and chemically.

This process relies on:

  • Stomach acid

  • Digestive enzymes

  • Bile production

  • Coordinated movement through the digestive tract

If any part of this process is not functioning optimally, symptoms such as bloating, fullness, indigestion, and digestive discomfort may occur. Research published in Basic & Clinical Pharmacology & Toxicology highlights the important role stomach acid plays in protein digestion, nutrient absorption, and protecting against unwanted microorganisms entering the digestive tract. Although low stomach acid is often discussed in functional medicine, it is important not to assume it is present based on symptoms alone. However, digestive function remains an important consideration when assessing ongoing digestive complaints.

Could Fat Digestion Be Affecting Your Symptoms?

Many people associate digestive issues with carbohydrates, but fats can also play a role. Bile, which is produced by the liver and stored in the gallbladder, is essential for digesting and absorbing dietary fats.

When fat digestion is impaired, some people may experience:

  • Bloating after meals

  • Nausea after fatty foods

  • Loose stools

  • Floating stools

  • Digestive discomfort

Research into bile acid metabolism has shown that altered bile acid function may contribute to symptoms in some individuals with digestive disorders, particularly those with diarrhoea-predominant IBS.

What About The Gut Microbiome?

The gut microbiome contains trillions of bacteria, fungi, and other microorganisms that influence digestion, immune health, and metabolism. Over the past decade, research has consistently found differences between the gut microbiomes of people with IBS and those without digestive symptoms. A study published in Gut identified distinct microbial patterns in some individuals with IBS, suggesting that changes in the microbiome may influence symptom development. However, there is currently no single "IBS microbiome," which is why digestive symptoms are rarely explained by one bacterial imbalance alone.

Is There A Role For Candida?

Candida is one of the most talked-about topics online when it comes to gut health. The reality is more nuanced. Candida species naturally exist within the digestive tract and form part of the normal gut ecosystem. Scientists are increasingly studying the gut microbiome, which refers to the fungal community living within the gut. However, an overgrowth in candida can result in a range of different symptoms.

Could Inflammation Be Playing A Role?

IBS has traditionally been described as a non-inflammatory condition. However, modern research suggests that some individuals with IBS may experience low-grade inflammation and immune activation within the digestive tract. Researchers have identified subtle changes in immune cell activity, inflammatory signalling, and interactions between the gut lining and the immune system. These findings may help explain why symptoms such as abdominal pain, bloating, and food sensitivities can persist even when routine medical tests appear normal.

What Is "Leaky Gut"?

You may have heard the term "leaky gut" on social media or in health articles. In scientific research, the preferred term is increased intestinal permeability. The intestinal lining acts as a selective barrier, allowing nutrients to pass through while helping keep potentially harmful substances out.

Research published in Neurogastroenterology & Motility has found evidence of increased intestinal permeability in some individuals with IBS, particularly those with diarrhoea-predominant symptoms.

However, intestinal permeability is unlikely to be the sole cause of IBS and is better viewed as one potential piece of a much larger puzzle.

The Gut-Brain Connection

Perhaps one of the most fascinating discoveries in digestive health is the close relationship between the gut and the brain. The digestive tract contains its own nervous system and communicates continuously with the brain through the gut-brain axis. Research from University of California, Los Angeles and other leading institutions has demonstrated that stress, sleep, anxiety, and nervous system regulation can all influence digestive symptoms. This does not mean symptoms are "all in your head." Rather, it highlights that digestive health is influenced by both physical and neurological factors.

Looking Beyond The Diagnosis

For many people, the most helpful question isn't:

"Do I have IBS?"

It's:

"What factors could be contributing to my symptoms?"

Because while IBS is a valid diagnosis, it doesn't always explain why symptoms developed in the first place.

The answer may involve one factor.

More often, it involves several.

And that's why a personalised approach is so important.

No two digestive systems are exactly alike, and no two people with IBS have exactly the same story.

3 slices of toast with different toppings
Rosalie Collins

Rosalie Collins is a qualified nutritional therapist specialising in in IBS, gut health and digestive issues. Rosalie has a degree in Nutritional Therapy. Rosalie is a registered member of BANT (the British Association for Nutrition and Lifestyle Medicine) and the Complementary & Natural Healthcare Council (CNHC), reflecting my commitment to high professional and ethical standards in practice. Rosalie supports clients in improving their health and wellbeing through personalised, evidence-informed nutrition and lifestyle guidance tailored to individual needs. Rosalie Collins is based in Glasgow and Derbyshire, however she works with clients across the UK.

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